WISET-KWISE 2023 Global Mentoring program successfully held its orientation in May 2023, providing professional career guidance to science and engineering mentees from undergraduate to postdoc level. The program, led by experienced mentors, aims to empower the future of science and engineering by offering personalized guidance, expert resources, and networking opportunities. The orientation brought together mentees and mentors worldwide to share insights and build connections for professional growth. As the program continues, it will play a critical role in shaping the next generation of leaders and driving innovation in these fields.